A common compound: 31643-49-9, name is 4-Nitrophthalonitrile, belongs to nitriles-buliding-blocks compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below. 31643-49-9
General procedure: 4-nitrophthalonitrile (0.38 g, 1.92 mmol), 2,4,6-trimethylphenylamine (0.55 g, 1.92 mmol) and anhydrous DMF(15 mL) were added to a round bottom flask under a nitrogen atmosphere.A fine powder of anhydrous potassium carbonate (0.8 g,5.76 mmol) was added to this mixture. The resulting mixture was stirredat room temperature for 24 h. The crude product was collected by filtration,washedwith distilled water, and then recrystallized. The crude productwas recrystallized from THF-petroleum ether to afford a whitepowder.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 31643-49-9, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Medyouni, Rawdha; Elgabsi, Wissal; Naouali, Olfa; Romerosa, Antonio; Sulaiman Alayed, Abdullah; Baklouti, Lasaad; Hamdi, Naceur; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 167; (2016); p. 165 – 174;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts