Application of 64248-62-0, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 64248-62-0 as follows.
Into the 500 ml reaction flask, place 40 g (R)-2-(4-hydroxyphenoxy)propionic acid and 0.5 g ammonium bromide, and add 100 ml dimethyl formamide DMF and 50 ml toluene as solvent to dissolve it. After slowly adding potassium carbonate 70.7 g. After waiting for the reaction flask to not generate gas, add 30.5 g bromobutane. After 85 C reaction 7 hours, add 31 g 3,4-difluorobenzonitrile react for 5 h, then filtered and the filtrate, and 50 ml toluene after washing with the filtrate after the merger of the desolvation, drying the obtained cyhalofop 75.2 g, total reaction yield is 95.7%, the appearance is a white solid.
According to the analysis of related databases, 64248-62-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Jiangsu Yongkai Chemical Co., Ltd.; Jiang Yunxiang; Zhao Feisi; Dong Haitao; Chen Kuanxin; Wei Dongyu; (7 pag.)CN107253912; (2017); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts