Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1080-74-6, name is 2-(3-Oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile, This compound has unique chemical properties. The synthetic route is as follows., Formula: C12H6N2O
7.1. Under argon (Ar) protection, add 0.43 mmol (486 mg) of intermediate M1 to a 100 mL three-necked bottle.1.73 mmol (336 mg) of 2-(3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile and 30 mL of chloroform.7.2. Add 1 mL of pyridine to the flask and react at 65 C for 24 hours.The reaction was stopped, the solvent was spun off, the mixture was taken up in methanol and filtered to give a crude product.7.3. The crude product is separated and purified by column chromatography. The eluent is a mixed solution of dichloromethane and petroleum ether in a volume ratio of 1..1.A black solid of 450 mg was obtained in a yield: 70%. That is, the small molecule LS1.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1080-74-6.
Reference:
Patent; Xiangtan University; Shen Ping; Liang Jingtang; Yin Pan; Zheng Tao; Zeng Xiaoying; (32 pag.)CN110283184; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts