In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 6629-04-5, name is N-Cyanoacetylurethane belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: N-Cyanoacetylurethane
Take aniline (compound c) 0.08mol, concentrated hydrochloric acid 45mL, 120mL water to make it dissolve,The solution was cooled to below 0C, and a 60 mL aqueous solution containing 0.11 mol of sodium nitrite was added dropwise.During the dropwise addition, the temperature was maintained below 0 C., and the mixture was stirred dropwise for 0.5 h. Ethyl 2-cyano-2-acetylcarbamate (compound d) dissolved in 400 mL of ethanol was added dropwise and 0.09 molA mixture of 0.27 mol sodium acetate was incubated for 3 h.The solid precipitated from the reaction mixture is filtered and the cake is washed with water.The pale yellow product was dried to give intermediate e(ethyl ((Z)-[2-cyano-2-(2-phenylhydrazono)acetyl]carbamate).
The synthetic route of 6629-04-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Liaoning University; Liu Ju; Chen Ye; Wang Yang; Li Jun; Zhou Ziyun; (22 pag.)CN107652300; (2018); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts