Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 628-20-6, name is 4-Chlorobutyronitrile, A new synthetic method of this compound is introduced below., Product Details of 628-20-6
Stage A 4-(N,N-Dimethylamino)butyronitrile 420 g of dimethylamine are added to a solution, heated to 80 C., of 400 g of 4-chlorobutyronitrile in 1,200 ml of pure ethanol After 12 hours under reflux, the solvent is concentrated, 3 liters of ethyl ether are then added and the precipitate formed is removed The filtrate is concentrated and distilled at 12 mm Hg. Proton nuclear magnetic resonance spectrum (200 MHz, solvent CDCl3): 1.75 ppm,q,2H; 2.25 ppm,s,6H; 2.3-2.5 ppm,t+t,2H+2H
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Adir et Compagnie; US5077288; (1991); A;,
Nitrile – Wikipedia,
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