Electric Literature of 31643-49-9, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 31643-49-9, Name is 4-Nitrophthalonitrile, SMILES is C1=C(C(=CC=C1[N+](=O)[O-])C#N)C#N, belongs to nitriles-buliding-blocks compound. In a article, author is Shamanth, Sadashivamurthy, introduce new discover of the category.
T3P mediated intramolecular rearrangement of o-aminobenzamide to o-ureidobenzonitrile using isothiocyanates
Current work describes the environmentally benign approach for the synthesis of o-ureidobenzonitriles, from o-aminobenzamides and isothiocyanates using T3P. Here, the conversion of thiourea to urea and amide to nitrile take place simultaneously via unprecedented intramolecular rearrangement. This protocol is operationally facile and offers wide variety of o-ureidobenzonitriles at room temperature in good to excellent yields.
Electric Literature of 31643-49-9, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 31643-49-9.