Sources of common compounds: 2-Ethoxybenzonitrile

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6609-57-0, name is 2-Ethoxybenzonitrile, This compound has unique chemical properties. The synthetic route is as follows., Safety of 2-Ethoxybenzonitrile

NH4Cl (1.26 g, 23.52 mmoles) is introduced in a 100 ml round bottom flask and suspended in 16 ml of anhydrous toluene under argon atmosphere . The mixture is cooled in an ice bath and 2N Al (CH3) 3 (12 ml) in toluene are added dropwise, keeping under stirring for 30′ at room temperature. 2-Ethoxybenzonitrile (Ig) is added and the reaction is refluxed with stirring for 9 hours. Silica (0.8g) and then methanol (8 ml) are added to the mixture of reaction to eliminate the excess of Al (CH3) 3. The suspension is diluted with 8 ml of dichloromethane and then filtered washing the obtained solid several times with methanol .The filtered solution is acidified with cone. HCl and evaporated to dryness. The obtained residue is treated with 12 ml of a mixture of dichlorometane/methanol (9:1), filtered and the organic solution evaporated to dryness . The residue is washed with ether.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 6609-57-0.