Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 15666-97-4, name is Octyl 2-cyanoacetate, A new synthetic method of this compound is introduced below., Computed Properties of C11H19NO2
d) In a 20 mL one-necked flask,Compound 2 (0.15 g, 0.1 mmol)And n-octyl cyanoacetate (0.2 g, 1 mmol) were dissolved in 20 mL of dry chloroform,Piperidine (0.1 mL) was added under argon,Followed by heating to 60 C for 24 h.After the reaction is over,The mixture was poured into water,Extracted with dichloromethane,The organic phase was collected and dried to give the crude product,And the product was separated by silica gel column using petroleum ether: dichloromethane (2: 1 by volume)Recrystallization from chloroform and methanol gave the dark red solid product NDFP-CNCOO (30 mg, yield: 14.6%),The synthetic compound NDFP-CNCOO is characterized as follows:
The synthetic route of 15666-97-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Central South University; Peng Hongjian; Luan Xiangfeng; Feng Liuliu; Li Hang; Zou Yingping; (11 pag.)CN106939013; (2017); A;,
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