Application of 4897-25-0. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 5-Chloro-1-methyl-4-nitroimidazole, is researched, Molecular C4H4ClN3O2, CAS is 4897-25-0, about Pyrazolopyrimidine nucleosides. Part VIII. The synthesis of certain 4-substituted pyrazolo[3,4-d]pyrimidine nucleosides. Author is Montero, Jean Louis G.; Bhat, Ganapati A.; Panzica, Raymond P.; Townsend, Leroy B..
1-(β-D-ribofuranosyl)pyrazolo[3,4-d]pyrimidine-4-thione, obtained by a 3-step synthesis from allopurinol riboside, was treated with alkyl and aryl halides to provide the corresponding 4-alkylthio derivatives Pyrazolo[3,4-d]pyrimidine I was used for the preparation of the 4-methylamino, 4-dimethylamino, 4-hydrazino, and 4-hydroxyamino analogs.
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Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts