Month: March 2022

COA of Formula: C5H5NS. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Pyridine-4-thiol, is researched, Molecular C5H5NS, CAS is 4556-23-4, about Compatibility of fabrication of superhydrophobic surfaces and addition of inhibitors in designing corrosion prevention strategies for electrodeposited nickel in saline solutions. Author is Noorbakhsh Nezhad, Amir Hossein; Arefinia, Reza; Kashefi, Mehrdad; Davoodi, Ali; Hosseinpour, Saman.

The aim of this study is to assess the synergistic effect of two corrosion control strategies: application of an inhibitor and enhancing the surface superhydrophobicity, for protection of electrodeposited nickel in saline solutions For this purpose, 4-Mercaptopyridine (C5H5NS) was added to the synthetic sea water solution and its corrosion inhibition efficiency was evaluated on electrodeposited smooth bright nickel layer and nickel films with hierarchical micro/nano structure. Stearic acid was used to tune the wetting properties of nickel films, from hydrophilic to superhydrophobic. Contact angle measurement, SEM, and Fourier-transform IR spectroscopy were utilized in the characterization of deposited nickel layers. Potentiodynamic polarization and electrochem. impedance spectroscopy were employed to assess the corrosion inhibition performance of inhibitor on different nickel films. Our results indicate that simultaneous increase in the surface hydrophobicity and adsorption of corrosion inhibitor strategies does not yield a better corrosion resistance and that the most effective corrosion inhibition can be obtained on the bright smooth sample after a prolonged immersion in the corrosive solution Furthermore, we show that the contact angle alone cannot be used to indicate the corrosion inhibition capability of an inhibitor.

If you want to learn more about this compound(Pyridine-4-thiol)COA of Formula: C5H5NS, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(4556-23-4).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Bromo derivatives of 1-methylglyoxaline and the constitution of “”chloroxalmethylin””》. Authors are Balaban, I. E.; Pyman, F. L..The article about the compound:5-Chloro-1-methyl-4-nitroimidazolecas:4897-25-0,SMILESS:C1=NC(=C(Cl)[N]1C)[N+]([O-])=O).Name: 5-Chloro-1-methyl-4-nitroimidazole. Through the article, more information about this compound (cas:4897-25-0) is conveyed.

cf. C. A. 16, 2863. Bromination of 18 g. 1-methylglyoxaline in 60 cc. CHCl3 with 36 g. Br in 60 cc. CHCl3 at 5-10° gave 10.4 g. 2,4,5-tribromo-1-methylglyoxaline (I), m. 93-4.5° (Wallach, Ber. 16, 537, gives 88-9°), 0.49 g. (as picrate) of 4,5-dibromo-1-methylglyoxaline (II), m. 79-80°, and 23.3 g. (as picrate) of unchanged base. I.HCl, m. 190-200°, dissociates in H2O. I is recovered to the extent of 90% after heating with 1 mol. Na2SO3 in 20% aqueous solution for 5 hrs., 1% of II also being isolated. II was further prepared by heating 4,5-dibromo-1-methylglyoxaline with Me2SO4 and from (CONHMe)2 and PBr5 (7% and 11% with 1 and 2 mols. PBr5, resp.). II.HCl, crystallizing with 2 H2O, lost in vacuo over H2SO4, and then m. 179°; HNO3 salt, m. 153°; picrate, yellow, m. 148-9°, soluble in 6 parts hot EtOH or 30 parts boiling H2O. Methylation of 4(5)-bromoglyoxaline gives 51% III and 1.5% IV (ratio 34:1), separated by fractional crystallization of the picrates from EtOH. 5-Bromo-1-methylglyoxaline (III), b15 128°, m. 45-6°, deliquescent; HCl salt, needles with 0.5 H2O, lost at 100° and then m. 155°; HNO3 salt, anhydrous prisms, m. 155° (effervescence) soluble in 4 parts boiling H2O; H oxalate salt, needles with 0.5 H2O, lost in vacuo over H2SO4 and then m. 147°; picrate, yellow needles, m. 190°. The 4(?)-sulfonic acid, m. 284°, results in 78% yield; it is soluble in 55 parts boiling H2O, almost insoluble in cold H2O. Heating 0.38 g. of the acid with 5 cc. 30% H2SO4 for 3 hrs. at 170° gave 0.11 g. III (as picrate). The 4-nitro derivative (V) of III (80% yield), m. 180°, soluble in 85 parts boiling H2O; HCl salt, m. 155° and decomposed by H2O. V crystallines unchanged from aqueous picric acid. With aqueous Na2SO3 V yields 4-nitro-1-methylglyoxaline-5-sulfonic acid, m. 254° (decomposition); Na salt, fine needles. Hydrolysis of the acid by heating with 30% H2SO4 gives 4-nitro-1-methylglyoxaline; this establishes the orientation of these bases directly and of IV indirectly. III condenses with HCHO, by heating 6 hrs. at 130°, to give 5-bromo-2-hydroxymethyl-1-methylglyoxaline, m. 143° and soluble in 15 parts boiling H2O (yield, 42%); picrate, yellow needles, m. 165-6°. Reduction with HI and red P gives 1,2-dimethylglyoxaline. Either III or IV, heated with MeI, gives 4(5)-bromo-1,3-dimethylglyoxalinium iodide, m. 202-4°, soluble in 8 parts hot EtOH; distillation at 15 mm. and 235° gave 43% IV and some III. 4-Bromo-1-methylglyoxaline (IV) is an oil; HNO3 salt, prisms, m. 155°, soluble in about 3 parts boiling H2O; picrate, yellow needles, m. 179°, soluble in 7 parts hot EtOH. The 5(?)-sulfonic acid (yield, 77%) crystallines with 1 H2O, m. 256° (decomposition), soluble in 15 parts boiling H2O. The 5-nitro derivative (VI) (yield, 54%), m. 105°, soluble in 40 parts boiling H2O. Methylation of 7 g. 4(5)-bromo-5(4)nitroglyoxaline (VII), gave 1.7 g. VI and 1.4 g. unchanged material. Na2SO3 (20% aqueous solution) reacts with VII to give 4(5)-nitroglyoxaline-5(4)-sulfonic acid, decomposes 300° (yield, 88%); Na salt, fine needles. “”Chloroxalmethylin,”” prepared according to W., gives a HNO3 salt, m. 145° which, heated with concentrated H2SO4 1.5 hrs. at 100°, gives 5-chloro-4-nitro-1-methylglyoxaline, m. 147°, soluble in 40 parts boiling H2O; it is therefore 5-chloro-1-methylglyoxaline.

If you want to learn more about this compound(5-Chloro-1-methyl-4-nitroimidazole)Name: 5-Chloro-1-methyl-4-nitroimidazole, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(4897-25-0).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2,4,5-Triphenylimidazole(SMILESS: C1(C2=CC=CC=C2)=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N1,cas:484-47-9) is researched.Recommanded Product: 1116-98-9. The article 《Synthesis and characterization of a new polymeric catalyst and used for the synthesis of imidazole derivatives》 in relation to this compound, is published in Research on Chemical Intermediates. Let’s take a look at the latest research on this compound (cas:484-47-9).

Cross-linked poly(4-vinylpyridine) supported TiCl4 abbreviated as [P4-VP]-Ti(IV) as a new polymeric catalyst was easily prepared and characterized by using the X-ray spectroscopy, EDS, mapping, TGA/DTG and FTIR techniques. This catalyst was used for synthesis of imidazole derivatives via one-pot three-component condensation reaction of benzil, ammonium acetate and aldehydes. This protocol offers advantages such as short reaction time, simple reaction work-up with reusability of catalyst.

If you want to learn more about this compound(2,4,5-Triphenylimidazole)Quality Control of 2,4,5-Triphenylimidazole, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(484-47-9).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Recommanded Product: 5-Chloro-1-methyl-4-nitroimidazole. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 5-Chloro-1-methyl-4-nitroimidazole, is researched, Molecular C4H4ClN3O2, CAS is 4897-25-0, about Synthesis of 6-(1-methyl-4-nitro-5-[4,5-14C]-imidazolyl]thiopurine (azathioprine). Author is Yeowell, Heather N.; Elion, Gertrude B..

Steps in the radioactive synthesis are similar to those used in the preparation of unlabeled azathioprine. N,N’-Dimethyloxamide -1,2-14C was cyclized by PCl5 to I (labeled C located by asterisk) which was nitrated to II. Reaction of II with 6-mercaptopurine gave 85% III or 23.7% radioactive product.

If you want to learn more about this compound(5-Chloro-1-methyl-4-nitroimidazole)Recommanded Product: 5-Chloro-1-methyl-4-nitroimidazole, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(4897-25-0).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (R)-3-(tert-Butoxycarbonyl)-5,5-dimethylthiazolidine-4-carboxylic acid, is researched, Molecular C11H19NO4S, CAS is 117918-23-7, about Structure-activity relationships of novel HIV-1 protease inhibitors containing the 3-amino-2-chlorobenzoyl-allophenylnorstatine structure, the main research direction is HIV1 protease inhibitor allophenylnorstatine derivative preparation structure activity.Computed Properties of C11H19NO4S.

A series of peptidomimetic human immunodeficiency virus (HIV) protease inhibitors containing substituted allophenylnorstatine (Apns: (2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid) were designed and synthesized. From the structure-activity relation of this series of compounds, SM-309515 was found to have potent antiviral activity against wild-type and resistant HIV-1s and to possess a desirable pharmacokinetic profile in dogs.

If you want to learn more about this compound((R)-3-(tert-Butoxycarbonyl)-5,5-dimethylthiazolidine-4-carboxylic acid)Computed Properties of C11H19NO4S, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(117918-23-7).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Quality Control of 2,4,5-Triphenylimidazole. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about Evidence for the Formation of 1,2-Dioxetane as a High-Energy Intermediate and Possible Chemiexcitation Pathways in the Chemiluminescence of Lophine Peroxides. Author is Boaro, Andreia; Reis, Roberta Albino; Silva, Carolina Santana; Melo, Diego Ulysses; Pinto, Alexander Garreta Goncalves Costa; Bartoloni, Fernando Heering.

A kinetic study of the chemiluminescent (CL) reaction mechanism of lophine-derived hydroperoxides and silyl peroxides induced by a base and fluoride, resp., provided evidence for the formation of a 1,2-dioxetane as a high-energy intermediate (HEI) of this CL transformation. This was postulated using a linear Hammett relationship, consistent with the formation of neg. charge on the transition state of HEI generation (ρ > 1). The decomposition of this HEI leads to chemiexcitation with overall low singlet excited state formation quantum yield (ΦS from 1.1 to 14.5 x 10-5 E mol-1); nonetheless, ΦS = 1.20 x 10-3 E mol-1 was observed with both peroxides substituted with bromine. The use of electron-donating substituents increases chemiexcitation efficiency, while it also reduces the rate for both formation and decomposition of the HEI. Different possible pathways for HEI decomposition and chemiexcitation are discussed in light of literature data from the perspective of the substituent effect. This system could be explored in the future for anal. and labeling purposes or for biol. oxidation through chemiexcitation.

If you want to learn more about this compound(2,4,5-Triphenylimidazole)Quality Control of 2,4,5-Triphenylimidazole, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(484-47-9).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Application of 117918-23-7. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: (R)-3-(tert-Butoxycarbonyl)-5,5-dimethylthiazolidine-4-carboxylic acid, is researched, Molecular C11H19NO4S, CAS is 117918-23-7, about Search for substrate-based inhibitors fitting the S2′ space of malarial aspartic protease plasmepsin II. Author is Kiso, Aiko; Hidaka, Koushi; Kimura, Tooru; Hayashi, Yoshio; Nezami, Azin; Freire, Ernesto; Kiso, Yoshiaki.

Plasmepsin (Plm) has been identified as an important target for the development of new antimalarial drugs, since its inhibition leads to the starvation of Plasmodium falciparum. A series of substrate-based dipeptide-type Plm II inhibitors containing the hydroxymethylcarbonyl isostere as a transition-state mimic were synthesized. The general design principle was provision of a conformationally restrained hydroxyl group (corresponding to the set residue at the P2′ position in native substrates) and a bulky unit to fit the S2′ pocket.

If you want to learn more about this compound((R)-3-(tert-Butoxycarbonyl)-5,5-dimethylthiazolidine-4-carboxylic acid)Application of 117918-23-7, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(117918-23-7).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Asha, T. M.; Sithambaresan, M.; Prathapachandra Kurup, M. R. published an article about the compound: Bis(acetylacetonato)dioxomolybdenum(VI)( cas:17524-05-9,SMILESS:O=[Mo+2]12(O=C([CH-]C(C)=O1)C)(O=C([CH-]C(C)=O2)C)=O ).Electric Literature of C10H14MoO6. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:17524-05-9) through the article.

Four new mononuclear dioxidomolybdenum(VI) complexes [MoO2LD] (D = methanol (1), ethanol (2), propanol (3) and [MoO2LD]2·D (D = 4-picoline (4))) were synthesized by the reaction of [MoO2(acac)2] with the thiosemicarbazone (H2L) derived from 3-ethoxy-2-hydroxybenzaldehyde and N4-(3-methoxyphenyl)thiosemicarbazone in presence of donor solvents like methanol, ethanol, propanol and 4-picoline. Crystal and mol. structures of the complexes were determined by single crystal x-ray diffraction anal. All the complexes portrayed similar mononuclear structures where the thiosemicarbazone is bonded to molybdenum(VI) ion as a bineg. tridendate agent. The molybdenum(VI) center in complexes 1-4 is six coordinate by the thiosemicarbazone, two oxido groups and an oxygen or nitrogen atom from the donor solvent mols. The complexes 1-4 exhibit oxygen atom transfer to PPh3 in acetonitrile medium in presence of N-N bidendate donors to form [Mo(IV)OL(N-N)] (N-N = 2-2′ bipyridine (5) or 1,10 phenanthroline (6)). The complexes were further characterized by elemental anal., spectroscopic methods (IR, UV-visible and 1H NMR) and TGA. The electrochem. behavior of these complexes were investigated for an insight into the redox behavior of the molybdenum(VI) centers in these complexes. Hirshfeld surface anal. was successfully employed for exploring the coordination geometries and various noncovalent interactions present in their crystal structures. Also, the catalytic abilities of 1-4 were tested for the oxidation of styrene using aqueous H2O2 as oxidant and NaHCO3 as co-catalyst. The reaction condition for all-out catalytic proficiency of the catalysts 1-4 were examined by studying the effect of various parameters such as the amount of catalyst, H2O2, co-catalyst (NaHCO3) and solvent (CH3CN) as well as temperature of the reaction. Almost 97-98% product selectivity was attained for the oxidation of styrene to styrene oxide.

If you want to learn more about this compound(Bis(acetylacetonato)dioxomolybdenum(VI))Electric Literature of C10H14MoO6, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(17524-05-9).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Soorni, Aboozar; Akrami, Amir Mohammad; Abolghasemi, Reza; Vahedi, Maryam published an article about the compound: Pyridine-4-thiol( cas:4556-23-4,SMILESS:SC1=CC=NC=C1 ).HPLC of Formula: 4556-23-4. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:4556-23-4) through the article.

Allium is one of the well-known genera of the Amaryllidaceae family, which contains over 780 species. Onions, garlic, leeks, and shallots are the most important species of this genus. Allium hirtifolium (shallot) is a rich source of proteins, carbohydrates, lipids, amino acids, and bioactive compounds such as organic sulfur compounds with an expansive range of biol. activities and medicinal attributes. To identify the putative compounds and genes involved in the organic sulfur pathway, we applied GC-MS and RNA-seq techniques for the bulb, stem, and flower tissues of A. hirtifolium. The essential oil anal. revealed the maximum amount of sulfur compounds in stem against flower and bulb tissues. Transcriptome profiling showed 6155, 6494, and 4259 DEGs for bulb vs. flower, bulb vs. stem, and flower vs. stem, resp. Overall, more genes were identified as being up-regulated rather than down-regulated in flower tissue compared to the stem and bulb tissues. Our findings in accordance with other results from different papers, suggest that carbohydrates are vital to bulb formation and development because a high number of identified DEGs (586 genes) were mapped to carbohydrate metabolism This study has detected the genes in the organic sulfur pathway and indicated that the alliinase gene shows a high variability among different tissues. In general, this study formed a useful genomic resource data to explore tissue-specific sulfur pathway in A. hirtifolium, which is helpful for functional breeding.

If you want to learn more about this compound(Pyridine-4-thiol)HPLC of Formula: 4556-23-4, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(4556-23-4).

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Recommanded Product: 2,4,5-Triphenylimidazole. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about Polysubstituted Imidazoles as LysoTracker Molecules: Their Synthesis via Iodine/H2O and Cell-Imaging Studies. Author is Adhikary, Saswati; Majumder, Leena; Pakrashy, Sourav; Srinath, Ravuri; Mukherjee, Kaustuv; Mandal, Chitra; Banerji, Biswadip.

An iodine-catalyzed, environmentally benign one-pot methodol. has been developed for the synthesis of diverse substituted imidazoles. This transition-metal-free, aerobic, water-mediated cyclization reaction is operationally simple and works well with different amines or aldehydes by multiple C-N bond formations with satisfactory yield. The methodol. is regioselective as well as scalable. These imidazole derivatives show excellent fluorescence properties both in the solid and solution phase, which is further extended to live-cell imaging. Due to the suitable fluorescence properties of these scaffolds, lysosome-directing groups are incorporated in two of these derivatized imidazoles to track intracellular lysosomes. Successfully, those mols. show bright blue fluorescence while detecting lysosomes in human or murine cells and can be considered to be rapid lysosome-staining probes.

Here is a brief introduction to this compound(484-47-9)Recommanded Product: 2,4,5-Triphenylimidazole, if you want to know about other compounds related to this compound(484-47-9), you can read my other articles.

Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts