So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Liu, Jie; Dodd, Robert H. researched the compound: tert-Butyl (2-(bromomethyl)phenyl)carbamate( cas:166329-43-7 ).Formula: C12H16BrNO2.They published the article 《Synthesis of 1,4-benzodiazepine-1-carbothioamides, bicyclic analogs of the TIBO-type anti-HIV agents》 about this compound( cas:166329-43-7 ) in Journal of Heterocyclic Chemistry. Keywords: TIBO analog preparation HIV virucide; benzodiazepinecarbothioamide TIBO analog preparation HIV. We’ll tell you more about this compound (cas:166329-43-7).
A series of N’-substituted 1,4-benzodiazepine-1-carbothioamides were prepared by reacting the precursor 1,4-benzodiazepine with the corresponding N-substituted isothiocyanates or with sodium thiocyanatotrifluoroacetic. Despite the structural resemblance of these mols. with the potent TIBO-type anti-HIV compound R82150, none of the compounds prepared displayed no anti-HIV activity in vitro.
There are many compounds similar to this compound(166329-43-7)Formula: C12H16BrNO2. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.
Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts