Product Details of 484-47-9. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2,4,5-Triphenylimidazole, is researched, Molecular C21H16N2, CAS is 484-47-9, about Base-promoted annulation of amidoximes with alkynes: simple access to 2,4-disubstituted imidazoles.
An efficient construction of imidazole ring by Cs2CO3-promoted annulation of amidoximes RC(NH2)=NOH (R = Me, Ph, 4-methylphenyl, 4-(trifluoromethyl)phenyl, thiophen-2-yl) with terminal alkynes R1CCR2 (R1 = H, Ph, 3-methylphenyl, trimethylsilyl; R2 = H, Ph, naphthalen-2-yl, thiophen-2-yl, etc.) in DMSO has been developed. This protocol provides a simple synthetic route with high atom-utilization for the synthesis of 2,4-disubstituted imidazoles I in good yields under transition-metal-free and ligand-free conditions. Internal alkynes can also undergo the annulation to give 2,4,5-trisubstituted imidazoles I.
In addition to the literature in the link below, there is a lot of literature about this compound(2,4,5-Triphenylimidazole)Product Details of 484-47-9, illustrating the importance and wide applicability of this compound(484-47-9).
Reference:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts