Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Name: 4-(2-Bromoacetyl)benzonitrile.
Diaconu, Dumitrela;Amariucai-Mantu, Dorina;Mangalagiu, Violeta;Antoci, Vasilichia;Zbancioc, Gheorghita;Mangalagiu, Ionel I. research published 《 Ultrasound assisted synthesis of hybrid quinoline-imidazole derivatives: a green synthetic approach》, the research content is summarized as follows. A green, straightforward and efficient study for obtaining hybrid quinoline-imidazole derivatives under ultrasound (US) irradiation as well as under conventional thermal heating (TH) was presented. The reaction pathway involved only two steps: the N-alkylation of imidazole ring and a Huisgen [3 + 2] dipolar cycloaddition reaction of ylides to di-Me acetylenedicarboxylate. For both types of reactions, a green workup procedure under US irradiation was presented. Under US irradiation, the N-alkylation of nitrogen atoms from the imidazole nucleus had outstanding benefits in terms of reaction time, energy consumption and yields and thereby could be considered an environmentally friendly method. Forty new hybrid quinoline-imidazole compounds were synthesized: 18 salts such as I [R = H, CN, Br, etc.], 8 dihydro-benzopyrrolo imidazolo quinoline II, 9 benzopyrrolo-imidazolo quinoline III and 5 dihydro-pyrroloquinoxaline quinoline cycloadducts IV.
Name: 4-(2-Bromoacetyl)benzonitrile, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4′ -cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4′ -cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts