Fare, Fiorenza; Dei Cas, Michele; Arnoldi, Sebastiano; Casagni, Eleonora; Visconti, Giacomo Luca; Parnisari, Giulia; Bolchi, Cristiano; Pallavicini, Marco; Gambaro, Veniero; Roda, Gabriella published the artcile< Determination of Methyldibromoglutaronitrile (MDBGN) in Skin Care Products by Gaschromatography-Mass Spectrometry Employing an Enhanced Matrix Removal (EMR) Lipid Clean-Up>, HPLC of Formula: 6136-93-2, the main research area is methyldibromoglutaronitrile skin care product gas chromatog mass spectrometry.
A new application of QuEChERS extraction followed by EMR-lipid cleanup and GC-MS anal. is proposed for skin care products. Method is applied to determine MDBGN, a preservative frequently used in cosmetic products before being banned for its allergic reactions. New validated procedure consists in extractingcosmetic products with acetonitrile, removing the lipid matrix and then water and solid particles from organic mixture by two dSPE in sequence and, lastly, analyzing extracts in GC-MS. Compared to classic liquid-liquid extraction with chloroform,method has superior features in terms of applicability to cosmetics, ease of use, working times optimization and, above all, reduction of anal. interfering lipidic constituents. Use of EMR-Lipid dSPE system followed by GC-MS anal. allows to trace and quantify a minimal amount of a banned preservative, MDBGN, in so-called “”complex”” matrixes, such as cosmetic creams. This system shows following advantages: much simpler use, as system provides tubes already packaged with clean-up phase, optimization of working times, and noticeable reduction of extraction impurities allowing cleaner extracts to be obtained. A new application of QuEChERS extraction followed by enhanced matrix removal-lipid cleanup and GC-MS anal. is proposed for skin care products. Compared to classic liquid-liquid extraction with chloroform (upper part),method has superior features in terms of applicability to cosmetics, ease of use, working times optimization and, above all, reduction of anal. interfering lipidic constituents .
European Journal of Lipid Science and Technology published new progress about Chamomile. 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, HPLC of Formula: 6136-93-2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts