Li, Haoyu; Liu, Yuliang; Chiba, Shunsuke published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Anti-Markovnikov hydroarylation of alkenes via polysulfide anion photocatalysis》.Formula: C7H3BrFN The article contains the following contents:
A protocol for anti-Markovnikov hydroarylation of alkenes, e.g., 2,3-dihydrofuran with aryl halides ArX (Ar = (4-CO2CH3)C6H4, 2-naphthyl, 5-cyanothiophen-2-yl, etc.; X = Br, Cl) has been developed using polysulfide anions as photocatalysts in the presence of the Hantzsch ester and water under irradiation with visible light. The results came from multiple reactions, including the reaction of 4-Bromo-2-fluorobenzonitrile(cas: 105942-08-3Formula: C7H3BrFN)
4-Bromo-2-fluorobenzonitrile(cas:105942-08-3) is used as a reagent in the synthesis of picolinamide derivatives as a novel class of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors.Formula: C7H3BrFN 4-Bromo-2-fluorobenzonitrile is also used in the preparation of fluorinated CB2 receptor agonists for PET imaging.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts