Hora, J. published the artcile< The synthesis of bis-endo-2-(hydroxymethyl)-5-(4-imidazolylmethyl)bicyclo[2.2.2]octane and the corresponding cyclohexane analog>, Product Details of C6H11NO2, the main research area is bicyclooctane imidazolylmethyl; cyclohexane imidazolylmethyl; imidazole bicyclooctanyl; cyclization aminoacetal.
The imidazolylbicyclooctane I was prepared in 9 steps by cyclization of 3,4-dihydrobenzoic acid with H2C:CHCO2Me and conversion of the II (R = CO2H, R1 = CO2Me) to II (R = tetrahydropyranyl, R1 = CH2Br) which was treated with Mg and (EtO)2CHCN, followed by reduction formylation, cyclization with HCONH2. 3-Oxabicyclononane was treated with MeCOCl and the cis-1-(chloromethyl)-4-(hydroxymethyl)cyclohexane similarly converted to III.
Recueil des Travaux Chimiques des Pays-Bas published new progress about Cyclization. 6136-93-2 belongs to class nitriles-buliding-blocks, and the molecular formula is C6H11NO2, Product Details of C6H11NO2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts