Name: 4-FluorobenzonitrileIn 2021 ,《Highly Efficient Oxidative Cyanation of Aldehydes to Nitriles over Se,S,N-tri-Doped Hierarchically Porous Carbon Nanosheets》 was published in Angewandte Chemie, International Edition. The article was written by Hua, Manli; Song, Jinliang; Huang, Xin; Liu, Huizhen; Fan, Honglei; Wang, Weitao; He, Zhenhong; Liu, Zhaotie; Han, Buxing. The article contains the following contents:
A series of Se,S,N-tri-doped carbon nanosheets with a hierarchical porous structure was designed (denoted as Se,S,N-CNs-x, x represented the pyrolysis temperature). It was found that the obtained Se,S,N-CNs-1000 was very selective and efficient for oxidative cyanation of various aldehydes including those containing other oxidizable groups into the corresponding nitriles using ammonia as the nitrogen resource below 100°C. Detailed investigations revealed that the excellent performance of Se,S,N-CNs-1000 originated mainly from the graphitic-N species with lower electron d. and synergistic effect between the Se, S, N and C in the catalyst. Besides, the hierarchically porous structure could also promote the reaction. Notably, the unique feature of this metal-free catalyst was that it tolerated other oxidizable groups and showed no activity on further reaction of the products, thereby resulting in high selectivity. Based on the investigations, this is the first work for the synthesis of nitriles via oxidative cyanation of aldehydes over heterogeneous metal-free catalysts. In addition to this study using 4-Fluorobenzonitrile, there are many other studies that have used 4-Fluorobenzonitrile(cas: 1194-02-1Name: 4-Fluorobenzonitrile) was used in this study.
4-Fluorobenzonitrile(cas: 1194-02-1) is used as chemical intermediate, solvent for perfumes and pharmaceuticals, stabilizer for chlorinated solvents, HPLC analysis, catalyst and component of transition-metal complex catalysts.Name: 4-Fluorobenzonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts