The author of 《Polymorphism and thermodynamic functions of liquid crystalline material 4-cyano-3-fluorophenyl 4-butylbenzoate》 were Inaba, Akira; Suzuki, Hal; Massalska-Arodz, Maria; Rozwadowski, Tomasz. And the article was published in Journal of Chemical Thermodynamics in 2012. HPLC of Formula: 86776-52-5 The author mentioned the following in the article:
Heat capacity measurements were conducted between temperatures of 5 K and 360 K by adiabatic calorimetry for the liquid crystalline material 4-cyano-3-fluorophenyl 4-butylbenzoate to investigate the phase behavior and determine the thermodn. functions. Five phases are identified: the metastable nematic phase, its glass phase (T g = 210 K), stable crystal I (T fus = 288.43 K), a new metastable crystal (crystal II), and the isotropic liquid The enthalpy of fusion of crystal I is 22.22 kJ · mol-1, and the entropy is 76.91 J · K-1 · mol-1. Polarizing microscopy observations were also conducted between T = 100 K and 300 K to confirm the phase behavior. The m.p. of crystal II (T fus = 286 K) and the clearing temperature of the nematic phase (T c = 279.4 K) were obtained using a microscope. On the other hand, the enthalpy of the clearing transition (526 J · mol-1) and the entropy (1.88 J · K-1 · mol-1) were obtained from the thermodn. functions. The Debye temperature of crystal II (55.3 K) is significantly lower than that of crystal I (60.7 K), indicating that the phonon d. of states is considerably different between the two crystals. The existence of low-energy excitations in the nematic glass and a low-energy shift of the intramol. modes in crystal II are also identified. In the experiment, the researchers used many compounds, for example, 4-Cyano-3-fluorophenyl 4-butylbenzoate(cas: 86776-52-5HPLC of Formula: 86776-52-5)
4-Cyano-3-fluorophenyl 4-butylbenzoate(cas: 86776-52-5) is a member of aromaticfluorinated building blocks. Depending on which substituents are present, fluoroaromatic intermediates can be converted into fluorinated or fluorine-free commercial end products.Fluorine-containing aromatics have been incorporated into drugs (hypnotics, tranquilizers, antiinflammatory agents, analgesics, antibacterials).HPLC of Formula: 86776-52-5
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts