Jaime-Figueroa, Saul; Bond, Michael J.; Vergara, J. Ignacio; Swartzel, Jake C.; Crews, Craig M. published an article in 2021. The article was titled 《Synthesis of Isoquinolones by Sequential Suzuki Coupling of 2-Halobenzonitriles with Vinyl Boronate Followed by Cyclization》, and you may find the article in Journal of Organic Chemistry.Application of 2042-37-7 The information in the text is summarized as follows:
A novel, facile, and expeditious two-step synthesis of series of 3,4-unsubstituted isoquinolin-1(2H)-ones from a Suzuki cross-coupling between 2-halobenzonitriles and com. available vinyl boronate followed by platinum-catalyzed nitrile hydrolysis and cyclization was described. In the experimental materials used by the author, we found 2-Bromobenzonitrile(cas: 2042-37-7Application of 2042-37-7)
2-Bromobenzonitrile(cas: 2042-37-7) is used as a starting material to synthesize novel benzothiophene derivatives that were found to exhibit antibacterial and antifungal activity. It is commonly employed in reactions that require an electron-rich species to carry out nucleophilic substitution (or addition) reactions.Application of 2042-37-7
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts