Joy, F.; Peter, F.; Gokul, P. C.; Nizam, A.; Chinnam, S. published an article in 2022. The article was titled 《UV-Promoted Metal- and Photocatalyst-Free Direct Conversion of Aromatic Aldehydes to Nitriles》, and you may find the article in Russian Journal of Organic Chemistry.Quality Control of 4-Fluorobenzonitrile The information in the text is summarized as follows:
An efficient, simple and catalyst-free UV-induced functional group transformation of aromatic aldehydes to nitriles was reported. The developed strategy delivered various functionalized aromatic nitriles with high yields and purity. The UV irradiation activated the carbonyl group of aldehydes and lead to the formation of aldoxime intermediate, further resulting in the generation of nitriles. The striking highlights of the reported methodol. were simple reaction conditions, good yields, UV-promoted transformation and catalyst-free synthesis. Due to the above-mentioned advantages, the methodol. provided a hand towards environmentally friendly chem. synthesis. In the experiment, the researchers used many compounds, for example, 4-Fluorobenzonitrile(cas: 1194-02-1Quality Control of 4-Fluorobenzonitrile)
4-Fluorobenzonitrile(cas: 1194-02-1) is used in the synthesis of flurenones, pharmaceutical prerequisites, as well as opiod receptor antagonists.Quality Control of 4-Fluorobenzonitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts