In 2019,Organic Letters included an article by Janot, Christopher; Palamini, Pierre; Dobson, Benjamin C.; Muir, James; Aissa, Christophe. SDS of cas: 2042-37-7. The article was titled 《Palladium-Catalyzed Synthesis of Bis-Substituted Sulfoxonium Ylides》. The information in the text is summarized as follows:
α-Aryl-α-alkoxycarbonyl methylsulfoxonium ylides such as PhC-(CO2R)S+(:O)Me2 (R = Me, Et, Ph, Me3SiCH2CH2, t-BuMe2SiOCH2CH2OCH2CH2OCH2CH2) were prepared by palladium-catalyzed cross-coupling of α-sulfoxonium-substituted esters with aryl bromides and triflates and iodobenzene in the presence of either Pd(PPh3)4 or Pd2(dba)3 and t-Bu3P or XPhos. Sulfoxonium ylides were prepared from nicergoline and from the triflate ester of estrone. In the experiment, the researchers used many compounds, for example, 2-Bromobenzonitrile(cas: 2042-37-7SDS of cas: 2042-37-7)
2-Bromobenzonitrile(cas: 2042-37-7) is a precursor to the quinazolinones, a class of drugs used to treat autoimmune diseases and coronary heart disease. This substrate molecule undergoes a palladium-catalyzed coupling reaction to form an aromatic ring. The light emission from this reaction can be seen in the reaction solution.SDS of cas: 2042-37-7
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts