Jang, Jihoon team published research in Asian Journal of Organic Chemistry in 2021 | 105-34-0

Quality Control of 105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.

Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Quality Control of 105-34-0.

Jang, Jihoon;Kim, Dae Young research published ã€?Visible Light Photocatalytic Trifluoromethylation/SET Oxidation/Cycloaddition Sequences of 2-Vinyl Phenols: Multicomponent Synthesis of 4H-Chromenesã€? the research content is summarized as follows. Visible light-mediated photocatalytic trifluoromethylation, single electron transfer (SET) oxidation, and cycloaddition cascades of 2-vinyl phenols with Umemoto’s reagent and malononitrile were developed. This approach provided the multicomponent synthesis of trifluoromethylated 4H-chromenes I [R = H, 6-Me, 6,8-di-Br, etc.; R1 = CN, CO2Me, CO2t-Bu] via the in situ generation of o-quinone methides, followed by sequential cyclization.

Quality Control of 105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts