On June 15, 2005, Nishiyabu, Ryuhei; Anzenbacher, Pavel Jr. published an article.Recommanded Product: 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile The title of the article was Sensing of Antipyretic Carboxylates by Simple Chromogenic Calix[4]pyrroles. And the article contained the following:
A simple, two- or three-step method for the synthesis of chromogenic octamethyl calix[4]pyrrole-based (OMCP) sensors for anions was presented. Electrophilic aromatic substitution allows for converting the pyrrole moieties of OMCP into a dye. The formation of a sensor-anion complex results in partial charge transfer and a dramatic change in color. The absorption (UV-vis) and NMR titration experiments show that the chromogenic OMCPs sense anions administered as aqueous solutions, even at high ionic strength (∼0.1 M NaCl), while displaying selectivity for pyrophosphate and carboxylate anions. The experiments with polyurethane sensor films show a strong response for aqueous carboxylates, such as antipyretics naproxen ≈ ibuprofen > salicylate, without being biased by bicarbonate or carboxy termini of blood plasma proteins. The experimental process involved the reaction of 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile(cas: 2510-01-2).Recommanded Product: 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile
The Article related to antipyretic ibuprofen salicylate naproxen carboxylate chromogenic calixpyrrole preparation, chromogenic calix pyrrole sensor anion preparation, sensor anion complex chromogenic calixpyrrole preparation color change, polyurethane sensor film anion complex chromogenic calixpyrrole color change and other aspects.Recommanded Product: 2-(2,3-Dihydro-1H-inden-1-ylidene)malononitrile
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts