Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Synthetic Route of 105-34-0.
Kumar, Abhinav;Srivastava, Rajendra research published 《 Zirconium Phosphate Catalyzed Transformations of Biomass-Derived Furfural to Renewable Chemicals》, the research content is summarized as follows. This study deals with the development of an economical, ZrPO4 mediated, one-step catalytic transformation of biomass-derived furfural into synthetic intermediates that have the capability to replace the conventional petrochem.-derived synthetic building blocks. ZrPO4 is prepared via a highly energy-efficient process at ambient temperature in the eco-friendly ethanol medium. ZrPO4 exhibits an excellent activity in the transformation of furfural into furfuryl alc. via the eco-friendly, safe, alc. mediated transfer hydrogenation protocol. Furthermore, furfural is also efficiently converted into furfural-derived dihydropyrimidinone and 2-(furan-2-ylmethylene)malononitrile via multicomponent Biginelli and Knoevenagel condensation reactions, resp. Moreover, other structurally homologous biomass-derived reactants such as 5-hydroxymethyl furfural and 2,5-diformyl furan are also compared under the optimized reaction conditions along with conventional petrochem.-derived reactants such as benzaldehyde and 1-heptenal. The high activity of ZrPO4 is correlated with the acidity/basicity, pyridine FT-IR measurements, and reactant adsorption experiments The catalyst exhibits no significant change in the activity even after five recycles. A non-noble, metal catalyzed, economical, and sustainable process for furfuryl alc. production will certainly motivate chemists and researchers. One simple catalyst affording three functional renewable synthetic intermediates from furfural will attract a significant amount of attention of catalysis researchers and industrialists. The high adsorption of furfural and optimum basicity and the Lewis/Brodonsted acidity of simple and economical amorphous ZrPO4 are responsible for achieving the excellent activity in the synthesis of furfural-derived renewable chems.
Synthetic Route of 105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts