Luo, Han team published research in Journal of Organic Chemistry in | 105-34-0

Recommanded Product: Methyl 2-cyanoacetate, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.

Industrially, the main methods for producing nitriles are ammoxidation and hydrocyanation. 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Both routes are green in the sense that they do not generate stoichiometric amounts of salts. Recommanded Product: Methyl 2-cyanoacetate.

Luo, Han;Li, Yumeng;Zhang, Yuan;Lu, Qixing;An, Qiaoyu;Xu, Mingchuan;Li, Shanshan;Li, Jun;Li, Baosheng research published 《 Nucleophilic Aromatic Substitution of 5-Bromo-1,2,3-triazines with Phenols》, the research content is summarized as follows. Herein, a concerted nucleophilic aromatic substitution (SNAr) reaction of 5-bromo-1,2,3-triazines, I, was developed, in which the nonclassic mechanism of this reaction could be revealed by calculation Furthermore, the resulting 5-aryloxy-1,2,3-triazines II (R = H, Me) with phenols R1OH (R1 = Ph, naphthalen-1-yl, benzo[d][1,3]dioxol-5-yl, indol-5-yl, etc.) could be used as convenient precursors to access biol. important 3-aryloxy-pyridines III [Ar = Ph, pyridin-3-yl; R2 = Me, Ph, pyridin-2-yl; R3 = C(O)Me, COOMe, CN] in one-pot manner.

Recommanded Product: Methyl 2-cyanoacetate, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts