Inorganic compounds containing the −C≡N group are not called nitriles, but cyanides instead.105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Though both nitriles and cyanides can be derived from cyanide salts, most nitriles are not nearly as toxic. Application In Synthesis of 105-34-0.
Luo, Han;Lu, Qixing;Xu, Mingchuan;Gu, Mingxi;Li, Baosheng research published 《 Facile Access to α-Substituted β-Thio Enals from 1,2,3-Triazines and Thiols》, the research content is summarized as follows. Herein, a chemoselective cascade addition reaction was reported, which starts from 1,2,3-triazines and thiols to access several different α-substituted β thio enals and their derivatives C(O)C(R1)=CHSR2 [R1 = H, Me, Br, SC6H4, etc.; R2 = CO2Me, Ph, Bn, etc.] in a green and efficient synthesis. In terms of applications, readily available substrates, diversity of products, and mild reaction system made this strategy highly attractive.
105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., Application In Synthesis of 105-34-0
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts