Nitriles used to be known as cyanides; the smallest organic nitrile is ethanenitrile, CH3CN, (old name: methyl cyanide or acetonitrile – and sometimes now called ethanonitrile). 105-34-0, formula is C4H5NO2, Name is Methyl 2-cyanoacetate. Nitriles are found in many useful compounds, including methyl cyanoacrylate, used in super glue, and nitrile rubber, a nitrile-containing polymer used in latex-free laboratory and medical gloves. SDS of cas: 105-34-0.
Shang, Zhi-Hao;Zhang, Zhen-Xiao;Weng, Wei-Zhao;Wang, Yu-Fei;Cheng, Tian-Wei;Zhang, Qiu-Yi;Song, Li-Qun;Shao, Tian-Qi;Liu, Kai-Xuan;Zhu, Yan-Ping research published 《 A Metal- and Azide-free Oxidative Coupling Reaction for the Synthesis of [1,2,3]Triazolo[1,5-a]quinolines and their Application to Construct C-C and C-P Bonds, 2-Cyclopropylquinolines and Imidazo[1,5-a]quinolines》, the research content is summarized as follows. An iodine-promoted one-pot cascade oxidative annulation reaction was developed for the synthesis of [1,2,3]triazolo[1,5-a]quinolines I [R = H, 7-F, 8-Cl, etc.] from Me azaarenes and N-tosylhydrazines. The reaction has a broad substrate scope and could be easily scaled up to gram-scale. 1,2,3-Triazoles were an important skeletal structure for the construction of C-C and C-P bonds, 2-cyclopropylquinolines and imidazo[1,5-a]quinolines, for which different synthetic applications were explored.
SDS of cas: 105-34-0, Methyl cyanoacetate is an alkyl cyanoacetate ester.
Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It undergoes calcite or fluorite catalyzed Knövenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α -cyanocinnamic esters.
Methyl Cyanoacetate is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate (M287290); a compound used in the synthesis of DPP-IV inhibitors for treating type 2 diabetes., 105-34-0.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts