Month: October 2022

Bartlett, Robert T. et al. published their research in Journal of Medicinal Chemistry in 1981 |CAS: 5098-14-6

The Article related to isoguanosine analog pharmaceutical preparation, antiinflammatory isoguanosine analog preparation, heart rate isoguanosine analog preparation, allergy isoguanosine analog preparation, muscle relaxant isoguanosine analog preparation, antihypertensive isoguanosine analog preparation, hypothermia isoguanosine analog preparation, nucleoside pharmaceutical preparation and other aspects.Product Details of 5098-14-6

Bartlett, Robert T.; Cook, Alan F.; Holman, Michael J.; McComas, Warren W.; Nowoswait, Eugene F.; Poonian, Mohindar S.; Baird-Lambert, Judy A.; Baldo, Brian A.; Marwood, John F. published an article in 1981, the title of the article was Synthesis and pharmacological evaluation of a series of analogs of 1-methylisoguanosine.Product Details of 5098-14-6 And the article contains the following content:

Analogs of 1-methylisoguanosine (I, R = Me, R1 = H, R2 = OH) were evaluated as muscle relaxants, antiinflammatory agents, allergy inhibitors, and for cardiovascular activity. Cyclizing imidazole nucleoside II with RNCO (R = Et, Bu, octyl, Ph) and deprotecting gave I (R = Et, Bu, octyl, Ph; R1 = H, R2 = OH). Bromination of I (R = Me, R1 = H, R2 = OH) with Br2-H2O gave I (R = Me, R1 = Br, R2 = OH) which reacted with N2H4 to give I (R = Me, R1 = NHNH2, R2 = OH). This was cleaved with Raney Ni to give I (R = Me, R1 = NH2, R2 = OH). Deamination of 1-methylguanosine with NaNO2 in aqueous AcOH gave 1-methylxanthosine. Iodination of I (R = Me, R1 = H, R2 = OH) with Me(PhO)3P+I- gave I (R = Me, R1 = H, R2 = iodo) which was cyclized to III or deiodinated to I (R = Me, R1 = R2 = H). The phosphate ester I (R = Me, R1 = H, R2 = OPO32-) was prepared as well as cyclic phosphate IV. C-Nucleoside V was prepared from Me β-D-ribofuranosyl-1-carboximidate. Cyclizing the 9-(2-hydroxyethoxy)methyl analog of II with MeNCO gave acyclic analog VI. Similarly prepared was the β-D-arabinofuranosyl analog of I (R = Me, R1 = H, R2 = OH). The experimental process involved the reaction of 2-Aminomalononitrile 4-methylbenzenesulfonate(cas: 5098-14-6).Product Details of 5098-14-6

The Article related to isoguanosine analog pharmaceutical preparation, antiinflammatory isoguanosine analog preparation, heart rate isoguanosine analog preparation, allergy isoguanosine analog preparation, muscle relaxant isoguanosine analog preparation, antihypertensive isoguanosine analog preparation, hypothermia isoguanosine analog preparation, nucleoside pharmaceutical preparation and other aspects.Product Details of 5098-14-6

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Mannarsamy, Maruthupandi et al. published their research in Chemistry – An Asian Journal in 2022 |CAS: 75629-62-8

The Article related to preparation cyclic zinc hydroxyethylisopropylbenzimidazolthione coordination complex, crystal structure cyclic zinc hydroxyethylisopropylbenzimidazolthione coordination complex, thermal decomposition cyclic zinc hydroxyethylisopropylbenzimidazolthione coordination complex, knoevenagel condensation catalyst cyclic zinc hydroxyethylisopropylbenzimidazolthione coordination complex and other aspects.Application of 75629-62-8

On September 14, 2022, Mannarsamy, Maruthupandi; Nandeshwar, Muneshwar; Muduli, Gopendra; Prabusankar, Ganesan published an article.Application of 75629-62-8 The title of the article was Highly Active Cyclic Zinc(II) Thione Catalyst for C-C and C-N Bond Formation Reactions. And the article contained the following:

The first discrete seven-membered cyclic zinc(II) complex catalyzed room temperature Knoevenagel condensation reactions, and the synthesis of perimidine derivatives is reported under mild reaction conditions. The cyclic zinc(II) complex [(L)ZnBr2] (1) was isolated from the reaction between 1-(2-hydroxyethyl)-3-isopropyl-benzimidazol-2-thione (L, 2) and ZnBr2 (3). Complex 1 was characterized by different analytic techniques such as FTIR, CHNS, TGA, NMR, and SCXRD. The mononuclear zinc(II) complex 1 was used as a catalyst for Knoevenagel condensation reactions to isolate twenty different substituted methylene malononitriles with excellent yield. Besides, the zinc(II) thione complex 1 was used for the synthesis of 2,4-dihydroperimidine derivatives in a highly efficient manner. Catalyst 1 depicted wide substrate scopes. Overall, twenty different substituted methylene malononitriles and nine different perimidine derivatives were synthesized using catalyst 1 at room temperature The present study features a mild and fast synthetic approach along with excellent functional group tolerance. The experimental process involved the reaction of 2-((1H-Indol-3-yl)methylene)malononitrile(cas: 75629-62-8).Application of 75629-62-8

The Article related to preparation cyclic zinc hydroxyethylisopropylbenzimidazolthione coordination complex, crystal structure cyclic zinc hydroxyethylisopropylbenzimidazolthione coordination complex, thermal decomposition cyclic zinc hydroxyethylisopropylbenzimidazolthione coordination complex, knoevenagel condensation catalyst cyclic zinc hydroxyethylisopropylbenzimidazolthione coordination complex and other aspects.Application of 75629-62-8

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kook, Ga Young team published research in Journal of Organic Chemistry in 2022 | 3032-92-6

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Safety of 4-Ethynylbenzonitrile

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 3032-92-6, formula is C9H5N, Name is 4-Ethynylbenzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Safety of 4-Ethynylbenzonitrile.

Kook, Ga Young;Kim, Daegeun;Chae, Min Ki;Ko, Haye Min research published ã€?Rhodium(II)-Catalyzed Highly Selective 1,3-Insertion Reactions Using N-Sulfonyl-1,2,3-Triazoles with Heteroaryl Ethers or Heteroaryl Alcoholsã€? the research content is summarized as follows. The transformation of N-sulfonyl-1,2,3-triazoles via insertion/rearrangement was achieved using 2-hydroxybenzimidazole or 2-alkoxybenzothiazole over 3 mol % Rh2(Oct)4 for the synthesis of α-((1H-benzo[d]imidazol-2-yl)amino) ketones I [R1 = 3-chloropropyl, cyclohexen-1-yl, Ph, etc.; X = O, S, NH; R2 = n-Bu, Ph, 4-MeC6H4, etc.] or (Z)-2-alkoxy-2-phenylethenamines II [R3 = Me, Ph, Bn, etc.; X = O, S; Y = S, O]. This regio- and stereoselective reaction proceeds under mild conditions, was tolerant of functional groups, and had a broad substrate scope. Notably, while the general rhodium-catalyzed reaction involved sigmatropic rearrangement from an allyl vinyl ether, the present synthetic methodol. prevents rearrangement owing to the benzimidazole group, allowed access to (Z)-olefins.

3032-92-6, 4-Ethynylbenzonitrile is a simple benzyl alkyne compound potentially useful as a synthetic fragment and as a test compound for cross-coupling protocols. 4-Ethynylbenzonitrile has been described as a model compound for studying hydrogen bond formation in multifunctional molecules, as it contains four hydrogen bonding sites of which three are π-acceptors.

4-Ethynylbenzonitrile is a useful research compound. Its molecular formula is C9H5N and its molecular weight is 127.14 g/mol. The purity is usually 95%., Safety of 4-Ethynylbenzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kolesnikov, Timofey I. team published research in European Polymer Journal in 2021 | 31643-49-9

31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., Electric Literature of 31643-49-9

Nitrile is any organic compound with a −C≡N functional group. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Electric Literature of 31643-49-9.

Kolesnikov, Timofey I.;Orlova, Alexandra M.;Tsegelskaya, Anna Y.;Cherkaev, Georgij V.;Kechekyan, Alexander S.;Buzin, Alexander I.;Dmitryakov, Petr V.;Belousov, Sergey I.;Abramov, Igor G.;Serushkina, Olga V.;Kuznetsov, Alexander A. research published ã€?Dual-curing propargyl-phthalonitrile imide-based thermoset: Synthesis, characterization and curing behaviorã€? the research content is summarized as follows. Oligoimide containing propargyl and phthalonitrile groups in one mol. (OI-PR-PN) was synthesized by a facile and eco-friendly method in benzoic acid melt. To incorporate side propargyl groups into the polyimide backbone, a new monomer was developed – 5-(2-propyn-1-yloxy) benzene-1,3-diamine (PBD). The OI-PR-PN dual-curing behavior was studied by DSC and FT-IR methods. The curing of phthalonitrile groups can be promoted by the intermediates formed during the propargyl groups polymerization This allows crosslinking of phthalonitrile groups at 300-350°C in one component system. OI-PR-PN showed good solubility in low b.p. solvents and had low melt viscosity (up to 8 Pas at 250°C). The temperatures of 10% weight loss of the cross-linked OI-PR-PN and oligoimide containing only propargyl groups (OI-PR) are 496°C and 450°C correspondingly. The completely cured OI-PR-PN glass transition temperature measured by dynamic mech. anal. was 424°C with a storage modulus 4.2 GPa at 50°C. The possibility of crosslinking without using curing additives with a combination of excellent thermal and mech. properties indicates the potential of OI-PR-PN as a matrix for composite manufacturing

31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., Electric Literature of 31643-49-9

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kokuev, Aleksandr O. team published research in Tetrahedron Letters in 2021 | 20099-89-2

Synthetic Route of 20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Synthetic Route of 20099-89-2.

Kokuev, Aleksandr O.;Ioffe, Sema L.;Sukhorukov, Alexey Yu. research published ã€?Addition of malonic esters to azoalkenes generated in situ from α-bromo- and α-chlorohydrazonesã€? the research content is summarized as follows. Michael addition of malonic esters to azoalkenes, generated in situ from α-bromo- and α-chlorohydrazones, has been accomplished. Both aliphatic and aromatic substrates bearing different functional groups were tolerated. The use of a strong base (sodium hydride) for generation of azoalkenes and deprotonation of malonate was found to be essential for a successful coupling. Synthetic potential of the obtained β-hydrazonoalkylmalonates RNHN:C(R1)CH2CH(CO2R2)2 [R = Ac, Boc, Cbz, 2,4-(O2N)2C6H3; R1 = t-Bu, EtO2C, Ph, 2-naphthyl, 2-thienyl, etc.; R2 = Me, PhCH2] was demonstrated by their smooth conversion into five- and six-membered N-heterocycles, functionalized hydrazides, 2-(2-oxo-2-arylethyl)malonates and 2-arylethylmalonates.

Synthetic Route of 20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Klintworth, Robin team published research in Beilstein Journal of Organic Chemistry in 2021 | 20099-89-2

COA of Formula: C9H6BrNO, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. COA of Formula: C9H6BrNO.

Klintworth, Robin;Morgans, Garreth L.;Scalzullo, Stefania M.;de Koning, Charles B.;van Otterlo, Willem A. L.;Michael, Joseph P. research published ã€?Silica gel and microwave-promoted synthesis of dihydropyrrolizines and tetrahydroindolizines from enaminonesã€? the research content is summarized as follows. A wide range of N-(ethoxycarbonylmethyl)enaminones I (R = 4-O2NC6H4, thiophen-2-yl, tert-Bu, etc.), prepared by the Eschenmoser sulfide contraction between N-(ethoxycarbonylmethyl)pyrrolidine-2-thione and various bromomethyl aryl and heteroaryl ketones RC(O)CH2Br, underwent cyclization in the presence of silica gel to give Et 6-(hetero)aryl-2,3-dihydro-1H-pyrrolizine-5-carboxylates II within minutes upon microwave heating in xylene at 150°C. Instead of functioning as a nucleophile, the enaminone acted as an electrophile at its carbonyl group during the cyclization. Yields of the bicyclic products II were generally above 75%. The analogous microwave-assisted reaction to produce Et 2-aryl-5,6,7,8-tetrahydroindolizine-3-carboxylates III [R1 = Ph, 4-MeOC6H4,4-O2NC6H4] from Et 2-[2-(2-oxo-2-arylethylidene)piperidin-1-yl]acetates IV failed in nonpolar solvents, but occurred in ethanol at lower temperature and microwave power, although requiring much longer time. A possible mechanism for the cyclization is presented, and further functionalization of the newly created pyrrole ring in the dihydropyrrolizine core was described.

COA of Formula: C9H6BrNO, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., 20099-89-2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kim, Yoonbin team published research in Advanced Functional Materials in 2021 | 31643-49-9

Application In Synthesis of 31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 31643-49-9, formula is C8H3N3O2, Name is 4-Nitrophthalonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Application In Synthesis of 31643-49-9.

Kim, Yoonbin;Kim, Daekyu;Lee, Jeongyeon;Lee, Lawrence Yoon Suk;Ng, Dennis K. P. research published �Tuning the Electrochemical Properties of Polymeric Cobalt Phthalocyanines for Efficient Water Splitting� the research content is summarized as follows. Polymeric metal phthalocyanines have great potential as electrocatalysts, yet their incorporation on a current collector without losing the activity of metal centers remains a challenge. Herein, a new strategy for preparing a series of polymeric cobalt phthalocyanines containing S linkers (pCoPc-1) or SO2 linkers (pCoPc-2) and their tunable electrochem. properties are reported. The pCoPcs coated on various substrates show favorable electrocatalytic activities toward oxygen and hydrogen evolution reactions (OER and HER). Particularly, the pCoPc-1 layer on Co3O4 nanosheet arrays exerts a cooperative effect enhancing both the OER and HER performances, and the subsequent phosphorization (P@pCoPc-1/Co3O4|CC) significantly boosts the HER performance with enhanced hydrophilicity and conductivity The high permeability and stability reinforcement of the pCoPc-1 layer allow the phosphorization of underlying Co3O4 to CoP without degradation, which remarkably enhances OER and HER performances as manifested by low overpotentials of 320 and 120 mV at 10 mA cm-2, resp. When engaged as a bifunctional electrocatalyst for the overall water splitting, the P@pCoPc-1/Co3O4|CC requires a low cell voltage of 1.672 V at 10 mA cm-2, showing long-term durability and mech. robustness. This study demonstrates the collaborative catalytic role of polymeric macrocyclic compounds that offers versatile tunability and stability for various electrocatalytic reactions.

Application In Synthesis of 31643-49-9, 4-Nitrophthalonitrile, also known as 4-Nitrophthalonitrile, is a useful research compound. Its molecular formula is C8H3N3O2 and its molecular weight is 173.13 g/mol. The purity is usually > 95%.
4-Nitrophthalonitrile is a chemical substance that can be synthesized by the reaction of sodium carbonate with 3,4,5-trimethoxybenzyl alcohol. It can also be prepared using nitro phenol and sodium hydroxide. 4-Nitrophthalonitrile has been shown to have high photochemical activity in the presence of light. The frequency shift of its infrared spectrum is indicative of a nucleophilic addition reaction mechanism. 4-Nitrophthalonitrile has been used as an intermediate for producing other chemicals, such as herbicides and pharmaceuticals., 31643-49-9.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kim, Wansoo team published research in Journal of Organic Chemistry in 2021 | 20099-89-2

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., Safety of 4-(2-Bromoacetyl)benzonitrile

Nitriles are found in many useful compounds. Nitrile rubber is also widely used as automotive and other seals since it is resistant to fuels and oils. Organic compounds containing multiple nitrile groups are known as cyanocarbons. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile. Nitriles are found in many useful compounds. One of the most common occurrences of nitriles is in Nitrile rubber. Safety of 4-(2-Bromoacetyl)benzonitrile.

Kim, Wansoo;Kim, Hun Young;Oh, Kyungsoo research published �Oxidation Potential-Guided Electrochemical Radical-Radical Cross-Coupling Approaches to 3-Sulfonylated Imidazopyridines and Indolizines� the research content is summarized as follows. Oxidation potential-guided electrochem. radical-radical cross-coupling reactions between N-heteroarenes and sodium sulfinates have been established. Thus, simple cyclic voltammetry measurement of substrates predicts the likelihood of successful radical-radical coupling reactions, allowing the simple and direct synthetic access to 3-sulfonylated imidazopyridines and indolizines. The developed electrochem. radical-radical cross-coupling reactions to sulfonylated N-heteroarenes boast the green synthetic nature of the reactions that are oxidant- and metal-free.

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., Safety of 4-(2-Bromoacetyl)benzonitrile

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kim, Minsu team published research in ACS Applied Materials & Interfaces in 2021 | 1835-49-0

Recommanded Product: Tetrafluoroterephthalonitrile, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , 1835-49-0.

Nitrile is any organic compound with a −C≡N functional group. 1835-49-0, formula is C8F4N2, Name is Tetrafluoroterephthalonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Recommanded Product: Tetrafluoroterephthalonitrile.

Kim, Minsu;Lee, Seung Min;Jeon, Jun Woo;Movaghgharnezhad, Shirin;Jeong, Heeyoung;Moghaddam, Farbod;Mitchell, Daniel;Kang, Pilgyu;Kim, Byoung Gak research published �Photothermochemical Nanoassembly of 3D Porous Graphene and Palladium Nanoparticles for High-Performance Hydrogen Detection� the research content is summarized as follows. Hybrid materials comprising graphene and palladium nanoparticles (PdNPs) are desirable for high-performance hydrogen detection because of the high sp. surface area, electron mobility, and flexibility of graphene and the high electrochem. responsivity and reversibility of PdNPs. However, obtaining hybrid materials is energy-intensive and time-consuming. Here, a facile and rapid laser photothermochem. single-step processing method to synchronously produce a nanoassembly of three-dimensional porous graphene and PdNPs from polymer films is reported. Polymers with intrinsic microporosity show high solubility in volatile solvents and miscibility with inorganic materials, allowing the fabrication of homogeneous polymer films containing Pd ligands. The films are photothermally processed using a laser to generate a nanohybrid via photoinduced thermal and chem. processes. The nanohybrid exhibits four-times-enhanced elec. conductivity compared to plain porous graphene, high crystallinity, and coherent covalent metal bonds with a homogeneous size and distribution of PdNPs in hierarchical micro/meso/macroporous graphene structures, allowing high-performance hydrogen sensing (1 ppm) with outstanding mech. reliability, flexibility, and durability upon bending and twisting. The nanoassembly is integrated with a wireless sensing platform, and hydrogen leakage (1 ppm) is detected using a smart phone. This laser-based nanomanufg. of the nanoassembly can potentially be applied to wearable detector production platforms in the military and industry.

Recommanded Product: Tetrafluoroterephthalonitrile, Tetrafluoroterephthalonitrile can react with alkyl grignard reagents to form 4-alkyltetraflurorobenzonitriles. It acts as a four electron donor ligand. Tetrafluoroterephthalonitrile can be used to synthesize polymers of intrinsic microporosity. It has been used to study UV rearranged polymers of teh PIM-1 type membrane for the efficient separation of H2 and CO2.
Tetrafluoroterephthalonitrile reacts with alkyl Grignard reagents to form corresponding 4-alkyltetrafluorobenzonitriles. Tetrafluoroterephthalonitrile acts as a four-electron donor ligand and forms tungsten(II)η 2-nitrile complexes.
Tetrafluoroterephthalonitrile is a hydroxyl group-containing organic chemical compound . It has been used in analytical chemistry as a reagent for the determination of peptide binding constants and disulfide bonds. Tetrafluoroterephthalonitrile binds to nucleophilic sites on proteins, such as the pim-1 protein, and can be used to transport other molecules across cell membranes. In addition, it has been used to produce polymers for use in analytical chemistry. This chemical is also able to bind with magnetic particles under constant pressure conditions, which makes it useful for optical sensor applications. , 1835-49-0.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts

Kim, Beomsoo team published research in Magnetic Resonance in Chemistry in 2021 | 20099-89-2

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., Related Products of 20099-89-2

Nitrile is any organic compound with a −C≡N functional group. 20099-89-2, formula is C9H6BrNO, Name is 4-(2-Bromoacetyl)benzonitrile.The prefix cyano- is used interchangeably with the term nitrile in literature. Related Products of 20099-89-2.

Kim, Beomsoo;Ahn, Seunghyun;Lee, Youngshim;Koh, Dongsoo;Lim, Yoongho research published �1H and 13C NMR spectral assignments of nineteen 5-(3,5-dimethoxyphenyl)-3-(2-methoxyphenyl)-2-pyrazoline derivatives� the research content is summarized as follows. Nineteen novel derivatives containing a pyrazolinyl-thiazole or pyrazolinyl-thiazol-4-one moiety were designed and synthesized in this study. The NMR and HR/MS data reported herein can aid in identifying similar compounds in the future.

20099-89-2, 4-(2-Bromoacetyl)benzonitrile, also known as 2-Bromo-4�-cyanoacetophenone, is a useful research compound. Its molecular formula is C9H6BrNO and its molecular weight is 224.05 g/mol. The purity is usually 95%.
2-Bromo-4�-cyanoacetophenone can be synthesized from ethylbenzene via aerobic photooxidation using aqueous HBr.
4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors., Related Products of 20099-89-2

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts