On January 24, 2012, Delisser, Vern; Hedberg, Martin; Jansson, Annette; Raadevik, Andreas; Ryberg, Per; Thiering, Swantje published a patent.Synthetic Route of 34662-29-8 The title of the patent was Process for the manufacturing of the compound 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1h-indole-5-carbonitrile 701. And the patent contained the following:
The present invention relates to a new process for the manufacture of the compound 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile as a free base and pharmaceutically acceptable salts thereof, particularly the 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile citrate, and to new intermediates prepared in said process suitable for large scale manufacturing of said compound The experimental process involved the reaction of 3-Chloro-4-nitrobenzonitrile(cas: 34662-29-8).Synthetic Route of 34662-29-8
The Article related to preparation morpholin indole citrate, Heterocyclic Compounds (More Than One Hetero Atom): Other 6-Membered Rings, Two Hetero Atoms and other aspects.Synthetic Route of 34662-29-8
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts