Jain, Shubha; Reddy, B. Nagi; Rao, K. Sambasiva; Neeliah, G. published an article in 2010, the title of the article was Microwave assisted synthesis of indole substituted alkenes using Knoevenagel condensation reaction and their antibacterial activity study.Computed Properties of 75629-62-8 And the article contains the following content:
The reaction rate of the Knoevenagel condensation can be dramatically enhanced by irradiating the reaction mixture containing an 3-indolealdehyde, active methylene compound, L-proline and PhCl using a com. microwave oven. Several Knoevenagel condensation products were synthesized within 5-17 min in good yields. The new compounds were also screened for antibacterial activity. The experimental process involved the reaction of 2-((1H-Indol-3-yl)methylene)malononitrile(cas: 75629-62-8).Computed Properties of 75629-62-8
The Article related to indole active methylene knoevenagel condensation microwave, indolyl alkene preparation antibacterial, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Computed Properties of 75629-62-8
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts