On April 26, 2018, Lee, Jennifer; Burnette, Pearlie; Chellappan, Srikumar; Barczak, Nicholas; Conti, Chiara; Escobedo, Jaime A.; Han, Bingsong; Lancia, David R., Jr.; Liu, Cuixian; Martin, Matthew W.; Ng, Pui Yee; Rudnitskaya, Aleksandra; Thomason, Jennifer R.; Zheng, Xiaozhang published a patent.Synthetic Route of 882978-62-3 The title of the patent was Methods using histone deacetylase 11 (HDAC11) inhibitors for treating proliferative diseases. And the patent contained the following:
The present invention provides methods and uses of inhibitors of histone deacetylase 11 (HDAC11) in the treatment of diseases and/or disorders, such as, for example, cell proliferative diseases. The experimental process involved the reaction of 4,5-Diamino-2-(trifluoromethyl)benzonitrile(cas: 882978-62-3).Synthetic Route of 882978-62-3
The Article related to hdac11 inhibitor cell proliferative disorder treatment, Pharmacology: Effects Of Neoplasm Inhibitors and Cytotoxic Agents and other aspects.Synthetic Route of 882978-62-3
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts