On May 31, 2020, Vitkovska, Viktorija; Zogota, Rimants; Kalnins, Toms; Zelencova, Diana; Suna, Edgars published an article.Computed Properties of 5098-14-6 The title of the article was Aliphatic chain-containing macrocycles as diazonamide A analogs. And the article contained the following:
Aliphatic alkyl chain-containing 12-14-membered macrocycles were designed as structural analogs of antimitotic natural product diazonamide A. Macrocycles were synthesized from 5-bromooxazole in 7 to 9 linear steps using Ru-catalyzed ring-closing metathesis as the key transformation. Heat effect of binding to α,β-tubulin tetramer (T4-RB3 complex) has been measured for the synthesized macrocycles by isothermal titration calorimetry method. The experimental process involved the reaction of 2-Aminomalononitrile 4-methylbenzenesulfonate(cas: 5098-14-6).Computed Properties of 5098-14-6
The Article related to diazonamide a analog aliphatic chain macrocycle preparation dissociation constant, Heterocyclic Compounds (More Than One Hetero Atom): Eight- and Higher-Membered Rings and other aspects.Computed Properties of 5098-14-6
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts