On September 8, 2016, Rajkumar, Vadla; Babu, Srinivasarao Arulananda; Padmavathi, Rayavarapu published an article.HPLC of Formula: 75629-62-8 The title of the article was Regio- and diastereoselective construction of a new set of functionalized pyrrolidine, spiropyrrolidine and spiropyrrolizidine scaffolds appended with aryl- and heteroaryl moieties via the azomethine ylide cycloadditions. And the article contained the following:
Highly regio- and diastereoselective syntheses of a new set of functionalized pyrrolidines, spiro-pyrrolidine/pyrrolizidine oxindoles, spiroacenaphthylenolyl-pyrrolidines/pyrrolizidines and spiro-1,3-indandionolyl-pyrrolidines/pyrrolizidines appended with various aryl- and heteroaryl moieties via the azomethine ylide cycloaddition reaction are reported. The Ag-catalyzed [3+2] cycloaddition of azomethine ylides derived from N-benzylideneiminoglycinates with various arylidene/heteroarylidenemalononitriles gave C-3,C-5-aryl/heteroaryl substituted C-4,C-4-dicyanopyrrolidine-2-carboxylate scaffolds with good regio- and diastereoselectivity. Further, the [3+2] cycloaddition of azomethine ylides derived from the decarboxylative reactions of different 1,2-dicarbonyls and α-amino acids with the indole/pyrrole-based dipolarophiles were studied. In the context of enriching the library of functionalized spiropyrrolidine- and spiropyrrolizidine scaffolds, these reactions led to the assembling of various spiro-pyrrolidine/pyrrolizidine oxindoles, spiroacenaphthylenolyl-pyrrolidines/pyrrolizidines and spiro-1,3-indandionolyl-pyrrolidines/pyrrolizidines appended with the indolyl- and pyrrolyl moieties at the C-3 position of the spiro-pyrrolidine/pyrrolizidine rings. The stereochem. of the cycloadducts was assigned based on the single crystal x-ray structures of representative major diastereomers obtained from the azomethine ylide cycloaddition reactions. The experimental process involved the reaction of 2-((1H-Indol-3-yl)methylene)malononitrile(cas: 75629-62-8).HPLC of Formula: 75629-62-8
The Article related to spiropyrrolidine spiropyrrolizidine aryl azomethine ylide cycloaddition regio diastereoselective preparation, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.HPLC of Formula: 75629-62-8
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts