Red’kin, R. G.; Shemchuk, L. A.; Chernikh, V. P.; Shishkin, O. V.; Shishkina, S. V. published an article in 2007, the title of the article was Synthesis of 4-(1H-indol-3-yl) derivatives of 2-amino-4H-pyran and 2-amino-4,6,7,8-tetrahydro-1H-quinolin-5-one.Recommanded Product: 75629-62-8 And the article contains the following content:
The novel heterocyclic compounds I (X = O, NR3; R1 = CN, CO2Et; R2 = H, Me; R3 = Ph, 4-MeC6H4, 4-HOC6H4, 4-MeOC6H4) were synthesized either by one-pot three-component condensation of 3-formylindole with active methylene compounds R1CH2CN and 1,3-diketone analogs, 3-HX-5,5-R22-substituted 2-cyclohexenones (II), or by two-step condensation of 3-formylindole with R1CH2CN followed by heterocyclization of the intermediate (indolyl)acrylonitriles with II. Acetylacetone, 4-hydroxycoumarin and 3-methyl-5-pyrazolone were also successfully used instead of II providing access to monocyclic and heterocycle-fused derivatives of I. The experimental process involved the reaction of 2-((1H-Indol-3-yl)methylene)malononitrile(cas: 75629-62-8).Recommanded Product: 75629-62-8
The Article related to quinolinone amino tetrahydro indolyl preparation, pyran amino indolyl preparation crystal structure, indole formyl condensation nitrile diketone, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazoles and other aspects.Recommanded Product: 75629-62-8
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts