On January 31, 1993, Yu, Euy Kyung; Ryu, Seoung Ryuall published an article.Recommanded Product: 2-Aminomalononitrile 4-methylbenzenesulfonate The title of the article was Studies on the synthesis of the 2-desamino and 2-desamino-2-methyl analogs of aminopterin intermediate at pteridine-C7 side chain. And the article contained the following:
Title aminopterin intermediates I (R = H, Me, NH2) were prepared from pyrazine II. Thus, dithiobisbenzoate III was reduced by NaBH4 and then treated with II to give pyrazine IV. The cyclization of IV with RC(:NH)NH2.HCl (R = H, Me, NH2) in the presence of NaOEt followed by basic hydrolysis gave I (R = H, Me, NH2). The experimental process involved the reaction of 2-Aminomalononitrile 4-methylbenzenesulfonate(cas: 5098-14-6).Recommanded Product: 2-Aminomalononitrile 4-methylbenzenesulfonate
The Article related to aminopterin intermediate pteridine c side chain, desamino analog aminopterin intermediate, Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Recommanded Product: 2-Aminomalononitrile 4-methylbenzenesulfonate
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts