Kowalska, Ewelina published the artcileVisible Light-Driven Reductive Azaarylation of Coumarin-3-carboxylic Acids, Safety of Picolinonitrile, the main research area is coumarinyl carboxylic acid cyanoazaarene iridium catalyst photochem decaboxylative azarylation; azaaryl chromanone preparation.
In the manuscript, reductive and decarboxylative azaarylation of coumarin-3-carboxylic acids was described. It utilizes the photocatalytic activation of (cyano)azaarenes in the presence of fac-Ir(ppy)3 as a photocatalyst. The methodol. was versatile and provides access to biol. relevant 4-substituted-chroman-2-ones. Visible light, photoredox catalyst, base, anhydrous solvent, and inert atm. constitute key parameters for the success of the described strategy. The developed methodol. involves a wide range of coumarin-3-carboxylic acids as well as (cyano)azaarenes.
Journal of Organic Chemistry published new progress about Arylation catalysts (photochem.). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Safety of Picolinonitrile.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts