Ma, Yueyue published the artcileDirect Arylation of α-Amino C(sp3)-H Bonds by Convergent Paired Electrolysis, Category: nitriles-buliding-blocks, the main research area is tertiary amine benzonitrile TEMPO catalyst electrochem arylation; benzylic amine preparation regioselective; C−H activation; arylation; cross-coupling; electrocatalysis; tertiary amines.
A metal-free convergent paired electrolysis strategy to synthesize benzylic amines through direct arylation of tertiary amines and benzonitrile derivatives at room temperature was developed. This TEMPO-mediated electrocatalytic reaction made full use of both anodic oxidation and cathodic reduction without metals or stoichiometric oxidants, thus showing great potential and advantages for practical synthesis. This convergent paired electrolysis method provided a straightforward and powerful means to activate C-H bonds and realize cross-coupling with cathodically generated species.
Angewandte Chemie, International Edition published new progress about Aralkyl amines Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, Category: nitriles-buliding-blocks.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts