Sheng, Zhi-Zheng published the artcileAlcohol amine-catalyzed CO2 conversion for the synthesis of quinazoline-2,4-(1H,3H)-dione in water, Formula: C7H6N2, the main research area is quinazoline dione preparation green chem; aminobenzonitrile carbon dioxide cyclization diethanolamine catalyst.
The conversion of CO2 to high value-added chems. in water using environmentally friendly and cost-effective catalysts is a very significant topic. In this work, a green method for the conversion of CO2 catalyzed by alc. amines has been developed. Alc. amines showed considerable activating ability to CO2 in the cyclization with 2-aminobenzonitrile to quinazoline-2,4(1H,3H)-dione in water. Notably, when diethanolamine (DEA) was used as the catalyst, 94% yield of quinazoline-2,4-(1H,3H)-dione could be achieved. A plausible mechanism has been proposed based on the 1H NMR, FT-IR anal. and DFT calculation The excellent catalytic performance is attributed to the combined effect of both the secondary amine and hydroxyl groups on alc. amines with the assistance of water in the formation of carbamate. Water plays a bi-functional role of solvent and co-catalyst in this catalytic process. Catalysts can be easily recovered and reused five times without significant loss of activity.
RSC Advances published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent) (amino). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Formula: C7H6N2.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts