Watanabe, Koh published the artcileReductive Cross-Coupling between Arylaldehydes and (Hetero)aryl Electrophiles Using Silylboronate Reductant, HPLC of Formula: 91-15-6, the main research area is diarylmethanol preparation; arylaldehyde heteroaryl electrophile cross coupling reaction.
A catalytic reductive cross-coupling between arylaldehydes ArCHO (Ar = Ph, 2-methylphenyl, naphthalen-2-yl, thiophen-2-yl, etc.) and aryl electrophiles RX (R = pyridin-2-yl, 3-methylpyridin-2-yl, 1,3-benzothiazol-2-yl, etc.; X = F, Cl, CN) using a silylboronate Si(Et)3(B)C(Me)2C(Me)2 as a terminal reductant is described. The reaction involves a copper-catalyzed silylboration of aldehydes affording the O-borylated α-silyl alcs. ArCH(R)OSi(Et)3 (I) followed by a nucleophilic aromatic substitution reaction with aryl electrophiles. This protocol offers a new opportunity to access 1,1-diarylmethanol derivatives (I) without rare metals or highly basic organometallic reagents.
European Journal of Organic Chemistry published new progress about Alcohols, silyl Role: SPN (Synthetic Preparation), PREP (Preparation). 91-15-6 belongs to class nitriles-buliding-blocks, name is Phthalonitrile, and the molecular formula is C8H4N2, HPLC of Formula: 91-15-6.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts