Cao, Zhenyu published the artcileSynthesis of 2-pyridyl oxazoline esters and their organocatalytic application to the enantioselective silane reduction of ketones, Category: nitriles-buliding-blocks, the main research area is pyridyl oxazoline ester chiral preparation organocatalyst; chiral alc preparation enantioselective; ketone reduction organocatalyst.
The synthesis of a number of novel chiral 2-pyridyl oxazoline esters I (R = Me, (2R)-2-methylbutanoyl, (pyridin-2-yl)carbonyl, (naphthalen-1-yl)carbonyl, etc.) is reported along with the use of these in the enantioselective organocatalytic reduction of ketones 4-R1C6H4C(O)CH3 (R1 = H, methyl). The chiral alcs. 4-R1C6H4CH(OH)CH3 were prepared in good to excellent yields (up to 99%) and found to catalyze the reduction reactions with good conversions (up to 99%) and in moderate to good enantioselectivities (up to 65% at high conversion and 70% with lower reactivity). The results give an insight into the effects of the catalyst structure on the selectivity observed in the reaction.
ARKIVOC (Gainesville, FL, United States) published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Category: nitriles-buliding-blocks.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts