Liu, Shitao published the artcileSubstituent-controlled chemoselective synthesis of multi-substituted pyridones via a one-pot three-component cascade reaction, Category: nitriles-buliding-blocks, the main research area is arylamine acetylenedicarboxylate ethoxymethylenemalonate cesium carbonate tandem three component cycloaddition; arylpyridone tricarboxylate preparation.
An efficient and concise one-pot strategy for the synthesis of multisubstituted pyridones via a one-pot three-component cascade reaction catalyzed by Cs2CO3 under solvent-free conditions was developed. The substituent-controlled chemoselective cycloaddition process involved steps including a Michael addition/ethanol elimination/intermol. cyclization sequence utilizing anilines, di-Et acetylenedicarboxylate, and di-Et ethoxymethylenemalonate. The synthesis various 2-pyridone and 4-pyridone species (41 examples) were obtained in good to excellent yields.
Organic & Biomolecular Chemistry published new progress about Aromatic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Category: nitriles-buliding-blocks.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts