Das, Asit Kumar published the artcileCu(OAc)2 catalysed aerobic oxidation of aldehydes to nitriles under ligand-free conditions, Synthetic Route of 1885-29-6, the main research area is aldehyde ammonium acetate copper catalyst oxidation reaction green chem; nitrile preparation.
An economically efficient and environmentally benign approach for the direct oxidative transformation of aldehydes to nitriles was developed using com. available non-toxic copper acetate as an inexpensive catalyst and ammonium acetate as the source of nitrogen in the presence of aerial oxygen as an eco-friendly oxidant under ligand-free conditions. The reactions were associated with high yield and various sensitive moieties like allyloxy, benzyloxy, t-butyldimethylsilyloxy, hetero-aryl, formyl, keto, chloro, bromo, methylenedioxy and cyano were well tolerated in the aforesaid method. The kinetic studies showed first order dependency on the aldehyde substrate in the reaction rate. The reaction was faster with the electron deficient aldehydes as confirmed by Hammett anal. Moreover, the present oxidative method was effective on larger scales showing potential for industrial application.
RSC Advances published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Synthetic Route of 1885-29-6.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts