Sajadi, Mahdieh Sadat’s team published research in Tetrahedron Letters in 2021-05-11 | CAS: 1885-29-6

Tetrahedron Letters published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Sajadi, Mahdieh Sadat published the artcilePalladium-catalyzed synthesis of novel trifluoromethylated quinazolinone, N-arylquinazoline and N-benzylquinazoline derivatives, Product Details of C7H6N2, the main research area is trifluoromethylated quinazolinone arylquinazoline benzylquinazoline preparation; aminobenzamide arylbenzimidamide trifluoroacetimidoyl chloride condensation cyclization palladium catalyst.

A simple and palladium-catalyzed procedure for synthesis of a novel series of potentially biol. active trifluoromethyl-substituted quinazolinones and N-arylquinazoline derivatives via condensation-cyclization reaction of 2-aminobenzamide, 2-amino-N’-arylbenzimidamides and 2-amino-N’-benzylbenzimidamides with trifluoroacetimidoyl chlorides has been developed. Noteworthy, this investigation showed the possible of transition-metal-catalyzed activation of trifluoroacetimidoyl chlorides as a carbon trifluoromethylated source for the synthesis of quinazolines and quinazolinone derivatives in good to excellent yields.

Tetrahedron Letters published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Product Details of C7H6N2.

Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts