Wen, Xiaowei published the artcile“”On water”” nano-Cu2O-catalyzed CO-free one-pot multicomponent cascade cyanation-annulation-aminolysis reaction toward phthalimides, Safety of 2-Aminobenzonitrile(Flakes or Chunks), the main research area is phthalimide maleimide preparation green chem copper oxide catalyst water; halobenzoic acid trimethylsilyl cyanide amine cascade cyanation annulation aminolysis.
An efficient nano-Cu2O-catalyzed cascade multicomponent reaction of 2-halobenzoic acids and trimethylsilyl cyanide with diverse amines was developed using water as a solvent, affording versatile N-substituted phthalimide derivatives I (R = C6H5, 4-H3CC6H4, 4-ClC6H4, etc.), II (R = Pr, 4-H3CC6H4, Bn, thiophen-2-yl methyl; R1 = 4-Me, 5-OMe, 4-F, etc.) in moderate to excellent yields. This novel strategy features carbon monoxide gas-free, environmentally benign, one-pot multistep transformation, com. available reagents, a cheap catalyst without any additives, wide functional group tolerance, and operational convenience.
Organic & Biomolecular Chemistry published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 1885-29-6 belongs to class nitriles-buliding-blocks, name is 2-Aminobenzonitrile(Flakes or Chunks), and the molecular formula is C7H6N2, Safety of 2-Aminobenzonitrile(Flakes or Chunks).
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts