Du, Huang-Chi published the artcileSynthesis of 5-substituted tetrazoles via DNA-conjugated nitrile, Computed Properties of 269411-71-4, the main research area is nitrile DNA conjugated sodium azide zinc cycloaddition; tetrazole substituted DNA conjugated preparation.
A zinc bromide-catalyzed synthesis of 5-substituted tetrazoles via DNA-conjugated nitriles using sodium azide has been developed. The protocol offered moderate to excellent yields of tetrazoles with a broad range of substrates, including a variety of functionalized aromatic, heterocyclic, and aliphatic nitriles. In addition, the electronic effect within the substrate scope was evaluated. DNA fidelity was assessed by ligation efficiency and amplifiability anal. The ability to generate tetrazoles expands the diversity of heterocycles in the preparation of DNA-encoded chem. libraries.
Organic & Biomolecular Chemistry published new progress about 1,3-Dipolar cycloaddition catalysts. 269411-71-4 belongs to class nitriles-buliding-blocks, name is 3-Amino-5-methoxybenzonitrile, and the molecular formula is C8H8N2O, Computed Properties of 269411-71-4.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts