Vorob’ev, Aleksey Yu. published the artcile1,3-Dipolar cycloaddition of cyanopyridines to heterocyclic N-imines: experimental and theoretical study, SDS of cas: 100-70-9, the main research area is triazolopyridine preparation; triazolophenanthroline preparation; triazoloquinolinol preparation; cyanopyridine heterocyclic imine dipolar cycloaddition.
A series of 2-pyridyl[1,2,4]triazolo[1,5-a]azines I [R = H, 4-pyridyl; R1 = H, 2-pyridyl; R2 = 2-pyridyl, 3-pyridyl, 4-pyridyl], II [R3 = 2-pyridyl, 3-pyridyl, 4-pyridyl], and III [R4 = 2-pyridyl, 3-pyridyl, 4-pyridyl] was synthesized by cycloaddition of cyanopyridines with N-aminoazinium mesitylenesulfonates under basic conditions (KOH/H2O). An improved protocol for pyridyl-substituted [1,2,4]triazolo[1,5-a]pyridines synthesis based on addition of H2O2 as internal oxidant had been suggested. In the case of quinolinium and isoquinolinium salts, only dimerization of the corresponding N-imines had been observed, while pyrazinium-N-imine had not shown any reactivity toward cycloaddition DFT studies showed that the cycloaddition proceeded through concerted mechanism.
Chemistry of Heterocyclic Compounds (New York, NY, United States) published new progress about 1,3-Dipolar cycloaddition reaction. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, SDS of cas: 100-70-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts