Donslund, Aske S. published the artcileAccess to β-Ketonitriles through Nickel-Catalyzed Carbonylative Coupling of α-Bromonitriles with Alkylzinc Reagents, SDS of cas: 100-70-9, the main research area is keto nitrile preparation; nickel catalyst carbonylative coupling bromonitrile alkylzinc bromide; alkylzinc reagents; beta-ketonitriles; carbonylation; isotope labeling; nickel catalysis.
In the presence of an N-quinolinylglycine nickel complex, α-bromonitriles such as PhCH2CH2CHBrCN and alkylzinc bromides such as n-propylzinc bromide underwent carbonylative coupling with near stoichiometric carbon monoxide in a two-chamber reactor to yield β-keto nitriles such as PhCH2CH2CH(CN)COn-Pr. The method was used to prepare 13C-labeled β-keto nitriles and heterocycles derived from them using a 13C-labeled carbon monoxide source.
Chemistry – A European Journal published new progress about Carbonylation (coupling). 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, SDS of cas: 100-70-9.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts