Shit, Manik published the artcileSupramolecular assembly of an Au(III) complex of 2-(3-phenyl-1H-1,2,4-triazol-5-yl)pyridine: Structure, biological studies and charge transportation, Category: nitriles-buliding-blocks, the main research area is crystal structure gold phenyltriazolylpyridine complex; gold phenyltriazolylpyridine preparation biol charge transport study.
An Au(III) complex, [Au(2-ptp)2]Cl (1) (2-ptp = 2-(3-phenyl-1H-1,2,4-triazol-5-yl)pyridine), was characterized by single-crystal x-ray diffraction technique and other spectroscopic data. Presence of different noncovalent interactions gives 3-dimensional supramol. structure. The complex 1 exhibits antibacterial activity against Gram-pos. (MIC) (Staphylococcus aureus [240μg/mL], Bacillus subtilis [645μg/mL]) and Gram-neg. ( Escherichia coli [270μg/mL], Enterococcus faecalis [820μg/mL], Klebsiella pneumonia [785μg/mL]) bacteria. Also, the toxicity of 1 was checked by MTT assay. The complex shows promising anticancer activity against Vero cells and the CC50 is 405μg/mL. The complex also shows improved conductivity (Λ) by one order difference on illumination (Λdark, 7.42 × 10-5 Sm-1 and Λillumination, 2.45 x 10-4 Sm-1).
Applied Organometallic Chemistry published new progress about Antibacterial agents. 100-70-9 belongs to class nitriles-buliding-blocks, name is Picolinonitrile, and the molecular formula is C6H4N2, Category: nitriles-buliding-blocks.
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts