Light-Promoted C-N Coupling of Aryl Halides with Nitroarenes was written by Li, Gang;Yang, Liu;Liu, Jian-Jun;Zhang, Wei;Cao, Rui;Wang, Chao;Zhang, Zunting;Xiao, Jianliang;Xue, Dong. And the article was included in Angewandte Chemie, International Edition in 2021.Reference of 319016-04-1 The following contents are mentioned in the article:
A photochem. C-N coupling of aryl halides with nitroarenes is demonstrated for the first time. Catalyzed by a NiII complex in the absence of any external photosensitizer, readily available nitroarenes undergo coupling with a variety of aryl halides, providing a step-economic extension to the widely used Buchwald-Hartwig C-N coupling reaction. The method tolerates coupling partners with steric-congestion and functional groups sensitive to bases and nucleophiles. Mechanistic studies suggest that the reaction proceeds via the addition of an aryl radical, generated from a NiI/NiIII cycle, to a nitrosoarene intermediate. This study involved multiple reactions and reactants, such as 4-((4-Methoxyphenyl)amino)benzonitrile (cas: 319016-04-1Reference of 319016-04-1).
4-((4-Methoxyphenyl)amino)benzonitrile (cas: 319016-04-1) belongs to nitriles. Nitrile compounds can be prepared by the incorporation of a cyanide source through C–C bond formation or by dehydration of primary carboxamides. Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion.Reference of 319016-04-1
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts