Intermolecular Reductive C-N Cross Coupling of Nitroarenes and Boronic Acids by PIII/PV=O Catalysis was written by Nykaza, Trevor V.;Cooper, Julian C.;Li, Gen;Mahieu, Nolwenn;Ramirez, Antonio;Luzung, Michael R.;Radosevich, Alexander T.. And the article was included in Journal of the American Chemical Society in 2018.SDS of cas: 319016-04-1 The following contents are mentioned in the article:
A main group-catalyzed method for the synthesis of aryl- and heteroarylamines by intermol. C-N coupling is reported. The method employs a small-ring organophosphorus-based catalyst (1,2,2,3,4,4-hexamethylphosphetane) and a terminal hydrosilane reductant (phenylsilane) to drive reductive intermol. coupling of nitro(hetero)arenes with boronic acids. Applications to the construction of both Csp2-N (from arylboronic acids) and Csp3-N bonds (from alkylboronic acids) are demonstrated; the reaction is stereospecific with respect to Csp3-N bond formation. The method constitutes a new route from readily available building blocks to valuable nitrogen-containing products with complementarity in both scope and chemoselectivity to existing catalytic C-N coupling methods. This study involved multiple reactions and reactants, such as 4-((4-Methoxyphenyl)amino)benzonitrile (cas: 319016-04-1SDS of cas: 319016-04-1).
4-((4-Methoxyphenyl)amino)benzonitrile (cas: 319016-04-1) belongs to nitriles. Nitriles are polar, as indicated by high dipole moments. As liquids, they have high relative permittivities, often in the 30s. Nitrile groups in organic compounds can undergo a variety of reactions depending on the reactants or conditions. A nitrile group can be hydrolyzed, reduced, or ejected from a molecule as a cyanide ion.SDS of cas: 319016-04-1
Referemce:
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts